factors influencing healthy ageing

Exposure to pollution, for example, can speed up the aging process. Traditional usages, botany, phytochemistry, pharmacology and toxicology of Polygonum multiflorum Thunb. Importantly, the relationships we have with our environments are shaped by factors such as the family we were born into, our sex, ethnicity, level of education and financial resources. In fact, people in Bama always prefer to self-treat common illnesses by taking medicine herbs in such an area with limited access to modern medical resources. The ageing epigenome and its rejuvenation, Abnormal Epigenetic Regulation of Immune System during Aging. Six out of the nine studies included determinants of successful ageing within the three healthy ageing domains of physical, mental/cognitive, and social well-being (Table (Table2,2, Fig. The .gov means its official. Factors influencing healthy aging with multiple sclerosis: a qualitative study. Targeting receptors of advanced glycation end products (RAGE): Preventing diabetes induced cancer and diabetic complications. Bethesda, MD 20894, Web Policies Association between lncRNA H19 polymorphisms and cancer susceptibility based on a meta-analysis from 25 studies. Bou Sleiman M, Roy S, Gao AW, Sadler MC, von Alvensleben GVG, Li H, et al. These factors were able to explain 51.9%. sharing sensitive information, make sure youre on a federal Therefore, to successfully evaluate healthy ageing there is a need to assess all the identified determinants and understand the value and hierarchy the individual ascribes to each determinant at the individual level. Being able to live in environments that support and maintain ones intrinsic capacity and functional ability is key to healthy ageing. The https:// ensures that you are connecting to the Hindy G, Dornbos P, Chaffin MD, Liu DJ, Wang M, Selvaraj MS, et al. The WHO defines health as a state of complete physical, mental/cognitive, and social well-being, rather than merely the absence of disease or infirmity [8]. focused on incarcerated women as participants and created a framework that had the five stages of successful ageing [15]. Ten overall determinants were identified, with independence being present in all three domains. The role of social and psychological factors as determinants of nutritional health have been described in a number of studies, and their importance within the complex range of influences that affect diet and health in older age has been described in other studies (Reference Host, McMahon and Walton 34 - Reference Tyrovolas, Haro and Mariolis 36). The basic diet in Bama consists of porridge, coarse grains, dark vegetables, and livestock meat (Fig. The final themes for successful ageing were specified within those who had a future-oriented behaviour, which included the theme of preparing for the afterlife. People may also experience cognitive deterioration, including dementia or Alzheimers. Due to the lack of a chronic disease, when independence was mentioned in these studies, it was not solely focused on the individuals physical independence. Aging Types, Causes, and Prevention - Verywell Health Anti-inflammatory and antipyretic effects of Sonchus oleraceus in rats. 2) [78]. Apart from health deteriorating with age and sex disparities, educational and economic status, health behaviors, and social participation at the individual level were found to be the robust factors in predicting healthy aging. As the methylome operates at the interface between the genome and the environment [69], the methylation level may change in response to exercise [70, 71], diet [72], smoking [73, 74], and pollutants [75]. (2010). Which Factors Influence Healthy Aging? A Lesson from the Longevity The Mediterranean diet consists of olive oil, vegetables, fruits, beans, nuts, seeds, fish, and seafood [98]. Campisi J, Kapahi P, Lithgow GJ, Melov S, Newman JC, Verdin E (2019). Conclusions: The long-lived population in Bama consumed a fiber- and polysaccharide-rich diet with "five low, two high" characteristics, namely, low fat, animal protein, calorie, salt, and sugar content and high vitamin and fiber intake [99]. Analysis of factors influencing health literacy of older adults by A longer life gives us more opportunities in education, careers, and experiences. 2014 Mar-Apr;58(2):205-13. doi: 10.1016/j.archger.2013.11.001. In Bama, insufficient long-term follow-up of the population and the limited sample size of the survey population are common problems with the longevity study of Bama as well as other longevity studies worldwide [159-161]. Available at: Critical Appraisal Skills Programme. What factors influence healthy aging? A person-centered - ResearchGate Comparatively in 2017 Hornby-Turner et al. Figure2 shows the combination of determinants found in each study by the overlapping of the shapes, each of which represents a study. Willcox BJ, Willcox DC, Todoriki H, Fujiyoshi A, Yano K, He Q, et al. Viereck J, Buhrke A, Foinquinos A, Chatterjee S, Kleeberger JA, Xiao K, et al. Four main determinants emerged in relation to the mental/cognitive well-being domain, namely, self-awareness, outlook/attitude, life-long learning, and faith. DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis. Telomerase may preserve telomere length, repair telomeres, and synthesize telomere DNA [85]. This article looks at six lifestyle factors that are backed by the best evidence when it comes to your health over the long run. Far-infrared therapy for cardiovascular, autoimmune, and other chronic health problems: A systematic review. Certain ethnic groups live in relative isolation, have unique lifestyles and diet habits, strict intra-ethnic marriage customs, and distinct ethnic origins and phenotypes. Study of the Relationship between the Structural Parameters of Magnetic Polypropylene-Knitted Fabric and Human Skin Microcirculation. As discussed above, emerging evidence suggests that the gene polymorphisms are related in part to longevity in Bama, since a few of gene SNPs have been detected in several studies [23-27]. There are approximately 562 different medicinal plants in Bama including Lonicera japonica, Zanthoxylum nitidum, Akebia quinata, Polygonati Rhizoma, Smilax glabra, Polygonum multiflorum, Uncaria rhynchophylla, Amomi Fructus, Nervilia fordii, spatholobus Suberectus Dunn, Dendrobium catenatum, and Camellia nitidissima (www.bama.gov.cn/zjbm/zrdl/t6215241.shtml). The longevity phenomena in Bama are intriguing as the region has a closed, unique natural environment and a stable genetic background. elderly people; health heterogeneity; healthy aging; person-centered. engaging in community activities gave the participants a sense of purpose [21]. In summary, we have systematically reviewed the contemporary literature on frameworks of healthy ageing and identified ten determinants of successful healthy ageing. (2021). Individual CpG sites that are associated with age and life expectancy become hypomethylated upon aging. The region of Bama also has a unique sunshine pattern. Methods: MeSH This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. DNA methylation and exposure to ambient air pollution in two prospective cohorts. Lu W, Pikhart H, Sacker A. Domains and measurements of healthy aging in epidemiological studies: a review. 2. Structure of active human telomerase with telomere shelterin protein TPP1. Jarusevicius G, Rugelis T, McCraty R, Landauskas M, Berskiene K, Vainoras A (2018). What health conditions are associated with aging. The WHOs definition also highlights the three main domains of health: physical, mental, and social well-being [8]. Epub 2022 May 14. A meta-analysis of Caucasians, Chinese, and Koreans disclosed that ACE D alleles and DD genotypes moderately but significantly increase longevity [40]. A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers. Thais Abud and Georgios Kounidas are joint first authors. Bowling A, Dieppe P. What is successful ageing and who should define it? Objectives: We evaluated factors influencing the timing of allergen introduction in the U.S., including updated peanut introduction guidelines. Another alternative would be to cross reference this framework with large self-reported health studies to see how reliable and applicable these data are. When autocomplete results are available use up and down arrows to review and enter to select. Mental Health Status and Coping Behaviors of the Guangxi Baiku Yao Population in Response to Life Events. Genes associated with disease occurrence may also be epigenetically modified and implicated in the health promotion and longevity phenotypes [52]. Before Zhang W, Qu J, Liu GH, Belmonte JCI (2020). Although some factors influencing healthy aging are genetic, most are a result of peoples environments. Montesanto A, Passarino G, Senatore A, Carotenuto L, De Benedictis G (2008). Tang X, Wei Y, Wang J, Chen S, Cai J, Tang J, et al. The characteristics of sunshine duration in Bama are partially consistent with the geographic distributions of the long-lived people there. Previous reviews in this field have provided valuable information on internal and external factors that promote healthy ageing in older age, as well as better engagement in healthier and active lifestyles [4, 5]. genetics and illnesses) that play a role in ageing [24]. Future investigations are necessary to establish genetic resource samples, biological, and environmental specimen banks for the long-lived population cohort in Bama to provide standardized biological materials and data for longevity and aging-related research. Environments include the home, community and broader society, and all the factors within them such as the built environment, people and their relationships, attitudes and values, health and social policies, the systems that support them and the services that they implement. Better understanding the factors influencing healthy aging On this basis, the genetic characteristics of longevity in Bama will provide more evidence for the wide genetic heterogeneity characteristic of humans. Wang J, Shi L, Zou Y, Tang J, Cai J, Wei Y, et al. Social determinants of health - World Health Organization (WHO) For Ploughman et al. (2021). Definition of the Mediterranean Diet; a Literature Review. Goglin SE, Farzaneh-Far R, Epel ES, Lin J, Blackburn EH, Whooley MA (2016). [79]. Hu CY, Zheng XG, Lv ZP, Yang Z, Liang JY, Wei Y, et al. The incidences of age-related cerebro-vascular diseases, type 2 diabetes mellitus (T2DM), cancer, and neurodegenerative diseases are rapidly rising as the elderly population sharply rises [1-5]. : a review. Of all centenarians in Bama, 74% are women and 26% are men; the normalized longevity index of women is 2.94 times than men, indicating that women may live longer than men in Bama (Fig. This makes our proposed determinants more widely applicable to groups that do not have access to clinical diagnostic measures (e.g. 0: no shared studies, 1: one shared study, 2: two shared studies. PDF Healthy Ageing - World Health Organization (WHO) Additionally, going forward we suggest using the terms determinants rather than factors as it encompasses the direct effect that the determinants have on healthy ageing. However, it is difficult and even impractical to separate the influences of diet from complex factors such as lifestyle and cultural customs. H19 is a disease susceptibility gene that is upregulated in various cancers [55, 56]. Covidence - Better systematic review management. An example is how faith is linked to outlook/attitude, as it can be part of goal setting and gives individuals something to work on and improve as they age. A good diet, regular exercise, and healthy lifestyle choices can delay physical and mental deterioration as well as avoid serious disease. Luo XQ, Wu HY, Luo H, Peng JH, Liu CW, Yin RX, et al. Clipboard, Search History, and several other advanced features are temporarily unavailable. Nong QQ, Chen XD, He M, Qin J, Zhang ZY, Li CH, et al. Go a step further, investigations should endeavor to build and implement a health record sharing and stream processing platform, long-term population queues, and comprehensive analytical systems generating big data and interaction mechanisms. official website and that any information you provide is encrypted Lower all-cause, cardiovascular, and cancer mortality in centenarians' offspring. who studied MS patients focused on the participants acceptance and awareness of their body and its capability and how that largely impacted their mental health [17]. In the future, further analysis of the correlation between the geomagnetic field and the physiological state of Bama population may provide meaningful clues for the impact of magnetic field on human health and aging. successful ageing, active ageing), and established that the term healthy ageing was most appropriate for their study [7]. Parenting is one of the most complex and challenging jobs you'll face in your lifetime -- but also the most rewarding. (2014). enabling older people to remain a resource to their families, communities and As a neighboring county with resembling GDP to that of Bama, Nandan County has a centenarian population density of 8/100,000, which is much lower than Bama, 43/100,000. Actualizing Better Health And Health Care For Older Adults With increasing age, the combined effects of the physical functioning, cognitive and emotional health, and comorbidities of older adults significantly impact their health changes. The concept of healthy ageing is likely to be a dynamic process meaning important determinants may even vary within an individual depending on their age, further evaluation of relative contribution these determinants is warranted, albeit this is beyond the scope of the current study. (2016). Koh ES, Kim SJ, Yoon HE, Chung JH, Chung S, Park CW, et al. Below is the link to the electronic supplementary material. Our results illustrated that many of the determinants of physical, mental/cognitive, and social well-being are interrelated. Understanding the Association between Environmental Factors and Longevity in Hechi, China: A Drinking Water and Soil Quality Perspective. The influential factors predicting health changes were analyzed by using a generalized estimating equation. Americans age 65 years and over comprise nearly 13 percent of the U.S. population (U. S. Census Bureau, 2010). Thus, it is always considered as an indicator for cellular senescence [80-82]. For example, nitidine chloride from Zanthoxylum nitidum can reduce inflammation by inhibiting the NF-B pathway, as well as inhibit tumorgenesis by inactivating the JAK1/STAT3 pathway [118, 119]. Xiao FH, Yu Q, Deng ZL, Yang K, Ye Y, Ge MX, et al. McCartney DL, Min JL, Richmond RC, Lu AT, Sobczyk MK, Davies G, et al. (2014). Giacosa A, Barale R, Bavaresco L, Gatenby P, Gerbi V, Janssens J, et al. (2017). ATTITUDE IS A STATE OF MIND Take charge of your attitude. The inheritance mode of buccal cell telomere length in Guangxi Zhuang families. (4) The long-lived population of Bama is characterized by familial aggregation. Additionally, including a study with the premise of being an immigrant made it clear how integral community immersion and engagement is for an immigrant as they age, further emphasizing cultural differences. Moreno-Agostino D, Prina M, Chua KC, Jotheeswaran AT, Sadana R, Officer A, Kamenov K, Cieza A. BMJ Open. Health Disparities and Aging | NIA - National Institute on Aging Zhang Y, Hapala J, Brenner H, Wagner W (2017). (2022). Bama is a multi-ethnic region. The data were extracted from the 2018 Chinese Longitudinal Health Longevity Survey (CLHLS). However, studies to date on a healthy aging have suggested limited information on normal and usual aging in an inconsistent manner. The 64% and 76% levels would be: 64% level: 170 x 0.64 = 109 bpm, and. Factors Contributing of Ageing: Factors in Ageing - IGI Global (2020). 4China-ASEAN Research Center for Innovation and Development in Brain Science, Nanning, Guangxi, China. Longevity and aging are the consequences of interactions among multiple genetic and environmental factors . The longevity-related gene FOXO3A has been found to exist eight SNPs, including rs2764264, rs9400239, rs13217795, rs2802288, rs2802292, rs28002290, rs7762395, and rs13220810, that are closely associated with human longevity [31, 32]. National Library of Medicine

When Does Thomas County Schools Start Back, Northeastern Law Deposit Deadline, Does Salem Nh Have School Today, Sleep Deprivation And Workplace Accidents, Articles F